Mycobacterium tuberculosis in central Ethiopia: drug sensitivity patterns and association with genotype
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چکیده
منابع مشابه
Mycobacterium tuberculosis in central Ethiopia: drug sensitivity patterns and association with genotype
Drug resistance tuberculosis (TB) and the emergence of multidrug resistant (MDR) isolates are significant concerns regarding TB control programs in several countries. This study was undertaken to evaluate the drug sensitivity of Mycobacterium tuberculosis and to assess its association with strains and lineages of M. tuberculosis. A total of 279 M. tuberculosis strains isolated from Central Ethi...
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Tuberculosis remains a major public health problem in both developing and developed countries. Drug-resistant tuberculosis is an increasing health problem and serious challenge to tuberculosis (TB) control programs. Information about the susceptibility pattern of Mycobacterium tuberculosis isolates against anti-tuberculosis drugs is an important aspect to TB control. The objectives of the s...
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To determine differences in the ability of Mycobacterium tuberculosis strains to withstand antituberculosis drug treatment, we compared the activity of antituberculosis drugs against susceptible Beijing and East-African/Indian genotype M. tuberculosis strains. Beijing genotype strains showed high rates of mutation within a wide range of drug concentrations, possibly explaining this genotype's a...
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BACKGROUND The comparison of Mycobacterium tuberculosis bacterial genotypes with phenotypic, demographic, geospatial and clinical data improves our understanding of how strain lineage influences the development of drug-resistance and the spread of tuberculosis. METHODS To investigate the association of Mycobacterium tuberculosis bacterial genotype with drug-resistance. Drug susceptibility tes...
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ژورنال
عنوان ژورنال: New Microbes and New Infections
سال: 2017
ISSN: 2052-2975
DOI: 10.1016/j.nmni.2017.02.003